The Hepatobiliary System. Fundamental and Pathological Mechanisms

Ultrasound of the Hepatobiliary System

Fundamental Genetic Processes and Mechanisms

Photoreactive derivatives of oligonucleotides containing arylazido groups at 5’-phosphate introduced by chemical synthesis extensively are used for the investigation of the components of DNA replication/repair systems by the methods of photoaffinity modification. We proposed that ATP derivatives bearing photoreactive substitutions at γ-phosphate might turn out substrates for T4 polynucleotide k...

SYSTEM MODELING WITH FUZZY MODELS: FUNDAMENTAL DEVELOPMENTS AND PERSPECTIVES

In this study, we offer a general view at the area of fuzzy modeling and fuzzymodels, identify the visible development phases and elaborate on a new and promisingdirections of system modeling by introducing a concept of granular models. Granularmodels, especially granular fuzzy models constitute an important generalization of existingfuzzy models and, in contrast to the existing models, generat...

Current Models for Predicting Drug-induced Cholestasis: The Role of Hepatobiliary Transport System

Drug-induced cholestasis is the main type of liver disorder accompanied by high morbidity and mortality. Evidence for the role of hepatobiliary pumps in the cholestasis patho-mechanism is constantly increasing. Recognition of the interactions of chemical agents with these transporters at the initial phases of drug discovery can help develop new drug candidates with low cholestasis potential. Th...

Relationship between Ethics and Fundamental Rights of Individuals in the Iranian Penal System

Background: The main purpose of criminal law must be to secure the basic human rights or fundamental rights of individuals. But the matter is the relationship between morality and human rights. For the purpose of the science of morality is to bring humanity to the highest degree of humanity, and the purpose of law is to achieve relative justice and to restore order in society. Equity is also a ...